This reaction occurs extremely rapidly and is short-lived, meaning that overall this isn’t the main way in which muscle cells generate ATP for contraction.
Phosphocreatine can anaerobically donate a phosphate to adenosine diphosphate (ADP) creating ATP, thus helping maintain the cells’ available ATP for contraction (if you remember your high school biology, this is the ATP-ADP cycle). Creatine is synthesized by the liver and kidney and is not prevalent in plants, so it wouldn’t naturally be a major component of a horse’s typical diet. Therefore, DMG and creatine are often found in supplements claiming to support muscle mass and recovery. The more ATP, the greater the energy available for muscle contraction, allowing for potentially increased power and stamina. Why would increasing creatine production or supplementing creatine improve performance?īecause the body can convert creatine to phosphocreatine, and phosphocreatine can be used to generate adenosine triphosphate (ATP), which is the energy currency of cells that allows muscle to contract. It’s thought to enhance muscle creatine levels. Dimethylglycine occurs naturally in animals and plants and is an intermediary product of choline metabolism (choline is a water-soluble vitamin involved in the metabolism and transport of fats).
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